Details for gene set NCI_IL2-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL2-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.6726594
Normalized Enrichment Score (NES)	-1.649473
Nominal p-value	0.0
FDR q-value	0.07817062
FWER p-Value	0.255

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RPS6	2060168	472	1.159	-0.0003	No
2	PPP2R5D	4010156 380408 5550112 5670162	524	1.084	0.0206	No
3	STAT5A	2680458	844	0.819	0.0212	No
4	MAPKAPK2	2850500	1108	0.621	0.0205	No
5	JAK3	70347 3290008	1394	0.500	0.0160	No
6	E2F1	5360093	1439	0.484	0.0242	No
7	CYLD	6590079	1543	0.439	0.0282	No
8	GRB2	6650398	1561	0.435	0.0367	No
9	BCL3	3990440	1936	0.326	0.0236	No
10	HRAS	1980551	2087	0.286	0.0217	No
11	IL2RA	6620450	2288	0.238	0.0161	No
12	UBE2D3	3190452	2324	0.231	0.0192	No
13	NFKB1	5420358	2339	0.229	0.0235	No
14	SOCS3	5550563	2346	0.227	0.0281	No
15	ELF1	4780450	2784	0.154	0.0078	No
16	PRKCZ	3780279	3157	0.115	-0.0098	No
17	TNF	6650603	3230	0.108	-0.0113	No
18	KRAS	2060170	3552	0.081	-0.0269	No
19	RAC1	4810687	3573	0.080	-0.0262	No
20	STAM	3850008 4760441	3689	0.071	-0.0309	No
21	MALT1	4670292	3761	0.066	-0.0333	No
22	PRKCA	6400551	3810	0.064	-0.0345	No
23	CCNA2	5290075	3843	0.062	-0.0349	No
24	REL	360707	3994	0.055	-0.0418	No
25	RPS6KB1	1450427 5080110 6200563	4372	0.041	-0.0613	No
26	BIRC2	2940435 4730020	4458	0.039	-0.0650	No
27	MAP2K2	4590601	4558	0.036	-0.0696	No
28	SOS1	7050338	4675	0.034	-0.0751	No
29	RASA1	1240315	4972	0.028	-0.0905	No
30	INSL3	4150092	5287	0.023	-0.1070	No
31	RIPK2	5050072 6290632	5362	0.023	-0.1105	No
32	MAPK11	130452 3120440 3610465	5433	0.022	-0.1138	No
33	IL4	6020537	5571	0.020	-0.1207	No
34	ATM	3610110 4050524	6095	0.015	-0.1487	No
35	PIK3R1	4730671	7181	0.009	-0.2071	No
36	RAN	2260446 4590647	7473	0.008	-0.2227	No
37	AKT1	5290746	7820	0.006	-0.2412	No
38	MYC	380541 4670170	8113	0.005	-0.2569	No
39	XPO1	540707	8292	0.005	-0.2664	No
40	MAP2K1	840739	8448	0.004	-0.2747	No
41	NRAS	6900577	8451	0.004	-0.2747	No
42	CALM1	380128	8853	0.003	-0.2963	No
43	PTPN11	2230100 2470180 6100528	9170	0.002	-0.3134	No
44	GAB2	1410280 2340520 4280040	9538	0.000	-0.3332	No
45	ARRB2	2060441	9730	-0.000	-0.3435	No
46	PIK3CA	6220129	9883	-0.001	-0.3517	No
47	SRC	580132	11138	-0.004	-0.4194	No
48	PRKCE	5700053	11223	-0.005	-0.4238	No
49	HSP90AA1	4560041 5220133 2120722	11225	-0.005	-0.4238	No
50	NOD2	2510050	11439	-0.006	-0.4352	No
51	IL2	1770725	11670	-0.006	-0.4474	No
52	FBXW11	6450632	11943	-0.008	-0.4620	No
53	IRS1	1190204	12178	-0.009	-0.4744	No
54	CHUK	7050736	12475	-0.010	-0.4902	No
55	IFNG	5670592	13089	-0.014	-0.5230	No
56	SYK	6940133	13759	-0.022	-0.5587	No
57	SGMS1	4780195	13788	-0.022	-0.5597	No
58	TERT	6660075	13893	-0.023	-0.5649	No
59	SHC1	2900731 3170504 6520537	14167	-0.028	-0.5790	No
60	FRAP1	2850037 6660010	14456	-0.034	-0.5938	No
61	JUN	840170	14517	-0.036	-0.5963	No
62	STAT5B	6200026	14758	-0.044	-0.6083	No
63	ERC1	1580170 2630717 6110762 6840280	14833	-0.047	-0.6113	No
64	MAPK1	3190193 6200253	14896	-0.050	-0.6135	No
65	FOS	1850315	14961	-0.053	-0.6158	No
66	FOXO3	2510484 4480451	14977	-0.054	-0.6155	No
67	STAM2	730731 2120377	15030	-0.056	-0.6171	No
68	CDK6	4920253	15139	-0.062	-0.6215	No
69	FASLG	2810044	15184	-0.066	-0.6225	No
70	PRF1	6660309	15276	-0.071	-0.6258	No
71	IKBKG	3450092 3840377 6590592	15354	-0.077	-0.6283	No
72	IKBKB	6840072	15396	-0.080	-0.6288	No
73	LTA	1740088	15537	-0.093	-0.6343	No
74	SP1	6590017	15961	-0.142	-0.6541	No
75	CALM2	6620463	16048	-0.154	-0.6554	No
76	MAPK3	580161 4780035	16052	-0.154	-0.6522	No
77	MAPK8	2640195	16060	-0.156	-0.6492	No
78	JAK1	5910746	16124	-0.165	-0.6490	No
79	FYN	2100468 4760520 4850687	16182	-0.174	-0.6483	No
80	IL2RB	4730072	16634	-0.253	-0.6671	Yes
81	BCL2	730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164	16684	-0.261	-0.6641	Yes
82	FOXP3	940707 1850692	16687	-0.262	-0.6585	Yes
83	NFKB2	2320670	16848	-0.300	-0.6606	Yes
84	CDK2	130484 2260301 4010088 5050110	16881	-0.308	-0.6556	Yes
85	MAPK14	5290731	16936	-0.320	-0.6516	Yes
86	RELA	3830075	16981	-0.335	-0.6467	Yes
87	RAF1	1770600	16999	-0.340	-0.6402	Yes
88	RELB	1400048	17053	-0.356	-0.6353	Yes
89	SMPD1	1410309 5550717	17178	-0.404	-0.6332	Yes
90	TRAF6	4810292 6200132	17300	-0.454	-0.6298	Yes
91	CALM3	3390288	17313	-0.460	-0.6204	Yes
92	LCK	3360142	17374	-0.493	-0.6129	Yes
93	MAP3K14	5890435	17378	-0.493	-0.6024	Yes
94	MYB	1660494 5860451 6130706	17459	-0.526	-0.5952	Yes
95	SOCS2	4760692	17500	-0.544	-0.5855	Yes
96	BCL10	2360397	17750	-0.680	-0.5842	Yes
97	NFKBIA	1570152	17914	-0.797	-0.5756	Yes
98	STAT3	460040 3710341	17921	-0.802	-0.5584	Yes
99	BCL2L1	1580452 4200152 5420484	17989	-0.859	-0.5434	Yes
100	DOK2	5340273	17990	-0.859	-0.5246	Yes
101	STAT1	6510204 6590553	18002	-0.879	-0.5061	Yes
102	IL2RG	4120273	18120	-1.031	-0.4900	Yes
103	UGCG	3420053	18155	-1.067	-0.4685	Yes
104	SOCS1	730139	18178	-1.112	-0.4455	Yes
105	PTK2B	4730411	18381	-1.636	-0.4208	Yes
106	CCND3	380528 730500	18383	-1.645	-0.3850	Yes
107	MAPK9	2060273 3780209 4070397	18415	-1.759	-0.3483	Yes
108	TNFAIP3	2900142	18472	-2.065	-0.3064	Yes
109	CISH	840315	18476	-2.102	-0.2607	Yes
110	CCND2	5340167	18548	-2.713	-0.2055	Yes
111	TNFRSF1A	1090390 6520735	18601	-3.812	-0.1252	Yes
112	RHOA	580142 5900131 5340450	18614	-5.784	0.0001	Yes